Cost 
$6,000.00
TAT 
8 weeks
CPT Code 
81479
Test Code 
1135
Test Methods 
Sequencing
Deletion/Duplication analysis
Specimen Types Accepted 
Blood
Saliva
Cultured Cells
Extracted DNA
Notes 
If sending saliva, 2 kits are required.
Any gene in the Comprehensive Lissencephaly Panel can also be ordered individually. Please contact us directly for cost and CPT code information.

Classic Lissencephaly (LIS) or Lissencephaly Type 1 is a smooth or nearly smooth cerebral surface caused by deficient neuronal migration. The spectrum of malformations ranges from complete agyria (absent gyri) to regional pachygyria to subcortical band heterotopia (SBH). Cobblestone lissencephaly (COB) previously designated as lissencephaly "type 2", is a brain malformation consisting of a complex cortical dysplasia with glioneuronal heterotopia on the brain surface, moderate to severe lissencephaly, dysmyelination, hypoplastic brainstem, and dysplastic cerebellum with cysts.

Our Comprehensive Lissencephaly panel includes sequencing and deletion/duplication analysis of 26 genes (ACTB, ACTG1, ARX, ATP6VOA2, B3GALNT2, B3GNT1, DCX, FKRP, FKTN, GMPPB, ISPD, LAMA2, LAMB1, LARGE, NDE1, PAFAH1B1, POMGNT1, POMGNT2, POMT1, POMT2, RELN, SNAP29, SRD5A3, TMEM5, TUBA1A, VLDLR) implicated in both classic and cobblestone lissencephaly.

Any gene in the Comprehensive Lissencephaly panel can also be ordered individually. Please contact us directly for cost and CPT code information.