Obesity occurs when abnormal amounts of triglycerides are stored in adipose tissuse and released as free fatty acids with detrimental effects. Dietary and lifestyle factors, and epigenetic modifications play a role in excess fat accumulation. Obesity is correlated with an increased risk of type-2-diabetes, cardiovascular disease, cancer and mortality. Obesity can be found as an isolated clinical finding as well as part of a mutli-systemic syndromic diagnosis.
Our Mongenic Obesity Sequencing Panel includes sequence analysis of the following 29 genes: MC4R, LEP, LEPR, POMC, NR0B2, BBS1, BBS2, ARL6, BBS4, BBS5, MKKS, BBS7, TTC8, BBS9, BBS10, TRIM32, BBS12, MKS1, CEP290, WDPCP, SDCCAG8, MAGEL2, SIM1, ALMS1, GNAS, NTRK2, PCSK1, PHF6, VPS13B.
Any gene in the Monogenic Obseity Sequencing Panel can also be ordered individually. Please contact us directly for cost and CPT code information.