Cost 
$540.00
TAT 
2 - 4 weeks
CPT Code 
81402
Test Code 
1105
Test Methods 
Microsatellite analysis
Specimen Types Accepted 
Blood
Saliva
Cultured Cells
Extracted DNA

Approximately 2-5% of patients with Angelman syndrome have paternal uniparental disomy (UPD) of chromosome 15.  These patients appear to be more mildly affected than those affected by a deletion.  Patients with paternal UPD may have fewer severe seizures and less severe microcephaly; almost 50% can speak a few words.

Approximately 25% of Prader-Willi syndrome is due to maternal UPD15.