A biallelic intronic expansion in the RFC1 gene has recently been identified in the majority of patients with CANVAS (Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome) and in a proportion of late onset ataxia patients. Re-analysis of our negative ataxia cases has demonstrated biallelic repeat expansions in RFC1 in ~5% of the cases. RFC1 repeat expansion analysis has been added to our Ataxia Repeat Expansion Panel at no additional cost, making this panel more comprehensive.  More details about our Ataxia Repeat Expansion Panel can be found here. RFC1 repeat expansion testing can also be ordered independently.