The UCGS hereditary cancer panel provides a comprehensive analysis of genes reported to be associated with malignancies related to hematologic (familial myelodysplastic syndrome/acute leukemia) breast, ovarian, colon, skin, endocrine, and others. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. This test is specifically designed to detect germline pathogenic variants and is not appropriate for the detection of somatic variants in tumor tissue. The panel includes sequence and deletion/duplication analysis of all the listed genes.
TAT
6 weeks
CPT Code
81443
Test Code
5144
Test Methods
Sequencing
Deletion/Duplication analysis
Specimen Types Accepted
Blood
Saliva
Buccal
Cultured Cells
Extracted DNA
Documents
Genes
Additional Information
Peripheral blood samples are not accepted for patients with a history of MDS/leukemia. Please send 2 T25 flasks of cultured fibroblasts instead.
Any gene in the Comprehensive Hereditary Cancer Panel can also be ordered individually. Please contact us directly for cost and CPT code information.
Variants within exon 15 of the PMS2 gene may not be analyzed or reported due to homology issues. Due to high homology, the sensitivity of this assay may be reduced in exon 2 and exons 12-15 of PMS2.