Monogenic diabetes mellitus includes a heterogeneous group of diabetes types that are caused by mutations in single genes. It is estimated that the monogenic forms of diabetes could represent as much as 1–2% of all cases of diabetes mellitus. The main phenotypes suggestive of an underlying monogenic cause include neonatal diabetes mellitus (NDM), maturity-onset diabetes of the young (MODY) and very rare diabetes-associated syndromes. NDM is diabetes diagnosed within the first 6 months of life and can be characterized as either permanent (PNDM), requiring lifelong treatment, or transient (TNDM), which typically resolves by 18 months of age.  NDM is rare with an incidence of approximately 1:1,000,000-260,000 live births. 

Institutional Price 
$3,000.00
TAT 
6 weeks
CPT Code 
81443
Test Code 
2140
Test Methods 
Sequencing
Deletion/Duplication analysis
Specimen Types Accepted 
Blood
Saliva
Buccal
Cultured Cells
Extracted DNA
Additional Information 
Any gene in the Neonatal Diabetes/MODY Panel can also be ordered individually (excluding the CEL gene). Please contact us directly for cost and CPT code information.