Weaver syndrome - another overgrowth disorder due to defects in histone modification
The genetic basis for Weaver syndrome recently has been identified (Tatton-Brown et al., Oncotarget, 2011, 2:1127-1133 and Gibson et al., Am. J. Hum. Genet. 2012, 90:110-118) allowing now for the possibility of genetic testing for this disorder. Weaver syndrome is a rare congenital developmental disorder that was first identified and described in two unrelated males in 1974 by Dr.