Monogenic diabetes mellitus includes a heterogeneous group of diabetes types that are caused by pathogenic variants in single genes. It is estimated that the monogenic forms of diabetes could represent as much as 5% of all cases of diabetes mellitus. The main phenotypes associated with a monogenic cause of diabetes include, maturity-onset diabetes of the young (MODY), neonatal diabetes mellitus (NDM), and very rare diabetes-associated syndromes.
The Monogenic Diabetes Panel includes sequence and deletion/duplication analysis of over 60 nuclear genes and the analysis of three mitochondrial mutations (m.3243A>G, m.8296A>G, m.14709T>C) that are associated with diabetes and deafness.
TAT
6 weeks
CPT Code
81443
Test Code
2140
Test Methods
Sequencing
Deletion/Duplication analysis
Specimen Types Accepted
Blood
Saliva
Buccal
Cultured Cells
Extracted DNA
Documents
Genes
Additional Information
Any gene in the Neonatal Diabetes/MODY Panel can also be ordered individually (excluding the CEL gene). Please contact us directly for cost and CPT code information.